Anti-Snail [2SN-5H6]
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| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Snail |
| Reactivity | Drosophila |
| Relevance | The Snail superfamily are zinc finger transcription factors. Overexpression of Snail1 can lead to cells undergoing EMT (epithelial to mesenchymal transition). This is achieved as Snail1 represses expression of E-cadherin, desmoplakin, muc-1, cytokeratin18 while enhances expression of vimentin and fibronectin. Snail1 therefore has a strong association with metastatic disease. |
| Host | Mouse |
| Immunogen | Recominant Drosophila Snail protein (aa 150-392) |
| Subclass | IgG1 kappa |
| Notes |
Recommend dilutions: 1/500 - 1/5000 Available in 100ul units |
| Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
References: 2 entries
Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.
Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL.
Europe PMC ID: 8371971
Add a reference
References: 2 entries
Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.
Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL.
Europe PMC ID: 8371971
Add a reference
References: 2 entries
Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.
Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL.
Add a reference
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