Anti-Snail [2SN-5H6]

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Applications	ELISA IF WB
Antigen/Gene or Protein Targets	Snail
Reactivity	Drosophila
Relevance	The Snail superfamily are zinc finger transcription factors. Overexpression of Snail1 can lead to cells undergoing EMT (epithelial to mesenchymal transition). This is achieved as Snail1 represses expression of E-cadherin, desmoplakin, muc-1, cytokeratin18 while enhances expression of vimentin and fibronectin. Snail1 therefore has a strong association with metastatic disease.
Host	Mouse
Immunogen	Recominant Drosophila Snail protein (aa 150-392)
Subclass	IgG1 kappa
Notes	Recommend dilutions: 1/500 - 1/5000 Available in 100ul units
Research Area	Cancer, Cardiovascular, Epigenetics & Nuclear Signalling

Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.

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Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.

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Mauhin et al. 1993. Nucleic Acids Res. 21(17):3951-7. PMID: 8371971.

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