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Anti-PPAR alpha [6PP-2B2]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  PPAR alpha, Peroxisome proliferator activated receptor alpha
Reactivity Human and Mouse
Relevance Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Host Mouse
Immunogen DLESPLSEEFLQEMGNI
Subclass IgG2a kappa
Notes No cross reactivity on PPARb and PPARg.

Available in 100ul units
Research Area Epigenetics & Nuclear Signalling

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