Anti-Acetyl Histone H4 (K5, K8, K12 or K16) [3HH4-2C2]
- Datasheet
- Reviews (0)
Info
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Histone H4 acetylated (K5, K8, K12 or K16) |
| Reactivity | Human and Mouse |
| Relevance | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Host | Mouse |
| Immunogen | MSGRG(acetyl-K)GG(acetyl-K)GLG(acetyl-K)GGA(acetyl-K)RHRKVLR(C) |
| Subclass | IgG1 kappa |
| Notes | Available in 100ul unit as ascites. |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 4 entries
Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.
UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Europe PMC ID: 11406595
Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.
ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro.
Europe PMC ID: 11106744
Add a reference
References: 4 entries
Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.
UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Europe PMC ID: 11406595
Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.
ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro.
Europe PMC ID: 11106744
Add a reference
References: 4 entries
Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.
UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.
ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro.
Add a reference
Have you used this reagent? Share your experience by submitting a review and help your fellow scientists.
Review this reagent