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Anti-Acetyl Histone H4 (K5, K8, K12 or K16) [3HH4-2C2]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  Histone H4 acetylated (K5, K8, K12 or K16) 
Reactivity Human and Mouse
Relevance Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host Mouse
Immunogen MSGRG(acetyl-K)GG(acetyl-K)GLG(acetyl-K)GGA(acetyl-K)RHRKVLR(C)
Subclass IgG1 kappa
Notes Available in 100ul unit as ascites.
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 2 entries

Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.

Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.


Add a reference

References: 2 entries

Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.

Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.


Add a reference

References: 2 entries

Brand et al. 2001. EMBO J. 20(12):3187-96. PMID: 11406595.

Dilworth et al. 2000. Mol Cell. 6(5):1049-58. PMID: 11106744.


Add a reference


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