- References (2)
- Inventor Info
|Applications||ELISA IHC IP WB|
|Antigen/Gene or Protein Targets||Nampt|
|Reactivity||Human and Mouse|
|Relevance||Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. NAMPT is localized in the cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.|
|Immunogen||Recombinant mouse Nampt|
|Recommended Growing Conditions||RPMI 5% FCS|
|Research Area||Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Immunology, Metabolism, Neurobiology|
There are 2 reference entries for this reagent.View All References
References: 2 entries
Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.
Europe PMC ID: 12555668
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