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Anti-Nampt [14A5]

Invented by Prof Oberdan LEO at Université Libre De Bruxelles

Info

Applications ELISA IHC IP WB
Antigen/Gene or Protein Targets Nampt
Reactivity Human and Mouse
Relevance Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. NAMPT is localized in the cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.
Host Rat
Immunogen Recombinant mouse Nampt
Subclass IgG2a kappa
Recommended Growing Conditions RPMI 5% FCS
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Immunology, Metabolism, Neurobiology

References: 2 entries

Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.

Europe PMC ID: 12555668


Add a reference

References: 2 entries

Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.

Europe PMC ID: 12555668


Add a reference

References: 2 entries

Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.


Add a reference


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