Anti-Nampt [14A5]

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Applications	ELISA IHC IP WB
Antigen/Gene or Protein Targets	Nampt
Reactivity	Human and Mouse
Relevance	Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. NAMPT is localized in the cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.
Host	Rat
Immunogen	Recombinant mouse Nampt
Subclass	IgG2a kappa
Recommended Growing Conditions	RPMI 5% FCS
Research Area	Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Immunology, Metabolism, Neurobiology

Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

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	Free University of Brussels
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	Prof Oberdan LEO
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	Free University of Brussels
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Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

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Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

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