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Anti-CEACAM1 [B3-17]

Info

Applications ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets CEACAM1
Synonyms Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; CD66a Antigen; BGP1; BGP; Biliary Glycoprotein 1; Antigen CD66
Reactivity Human
Relevance Carcinoembryonic antigen related cell adhesion molecules (CEACAM) (CD66a) belong to the immunoglobulin superfamily. They are highly glycosylated proteins with the typical N-terminal variable Ig-like domain followed by 0-6 constant Ig-like domains. A hydrophobic transmembrane domain with a cytoplasmic tail anchors CEACAM1 to the cell membrane. CEACAM1 is known as an epithelial tumour suppressor and an angiogenic growth factor.
Host Mouse
Immunogen A1/B-domains of CEACAM1
Subclass IgG1 kappa
Notes Disease associations: Cancer, inflammatory diseases (e.g. Multiple Sclerosis), autoimmune disease, infection and wound healing processes.

No cross reactivity with mouse and rat CEACAM
Research Area Cancer, Cell Type or Organelle Marker

References

There are 4 reference entries for this reagent.

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References: 4 entries

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.

Europe PMC ID: 24040308

Klaile et al. 2013. Respir Res. 14:85. PMID: 23941132.

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II int

Europe PMC ID: 23941132

Muturi et al. 2013. PLoS One. 8(9):e74654. PMID: 24040308.


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References: 4 entries

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.

Klaile et al. 2013. Respir Res. 14:85. PMID: 23941132.

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II int

Muturi et al. 2013. PLoS One. 8(9):e74654. PMID: 24040308.


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Inventor Information

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