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Anti-Trem-like 4 [16E5]

Invented at The Rockefeller University

Info

Applications FACS
Antigen/Gene or Protein Targets Trem-like 4
Synonyms Triggering Receptor Expressed On Myeloid Cells Like 4; TREM Like Transcript 4; TLT4
Reactivity Mouse
Relevance Antibody 16E5 binds to mouse Trem-like 4. Trem-like 4 is expressed on macrophages in the spleen, and dendritic cells, especially CD8+ dendritic cells. It is a member of the TREM family and a type I transmembrane protein consisting of a single extracellular V-type Ig-like domain, a transmembrane domain, and a short cytoplasmic domain.
Host Mouse
Immunogen A chimeric protein consisting of Trem-like 4 extracellular portion and human IgG1 Fc portion
Subclass IgG1 kappa
Myeloma Used P3X63Ag8
Research Area Apoptosis and Programmed Cell Death, Cell Type or Organelle Marker, Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Hemmi et al. 2009. J Immunol. 182(3):1278-86. PMID: 19155473.

A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells.

Europe PMC ID: 19155473


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References: 2 entries

Hemmi et al. 2009. J Immunol. 182(3):1278-86. PMID: 19155473.

A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells.


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Inventor Information

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