Anti-Keratin K1 [LHK1]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 151903 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | Keratin 1 |
| Reactivity | Human |
| Relevance | Reactivity on normal human skin sections is suprabasal up to the tratum corneum in interfollicular epidermis. The suprabasal in the upper outer root sheath are also reactive. Very good marker for suprabasal keratinocytes. |
| Host | Mouse |
| Immunogen | 13-amino acid (1 .75-kd) sequence (VRFVSTSYSGVTR) of the K1 polypeptide C terminus |
| Subclass | IgG2a kappa |
| Molecular Weight (kDa) | 68 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM 5% FCS |
| Strain | Balb/c |
| Research Area | Cell Signaling & Signal Transduction |
References: 8 entries
Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Europe PMC ID: 12598329
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.
Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes.
Europe PMC ID: 10084315
Machesney et al. 1998. Am J Pathol. 152(5):1133-41. PMID: 9588880.
IHC
Activated keratinocytes in the epidermis of hypertrophic scars.
Europe PMC ID: 9588880
Leigh et al. 1993. Br J Dermatol. 129(2):110-9. PMID: 7544603.
IHC
Monospecific monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) and to keratin 10 as markers of epidermal differentiation.
Europe PMC ID: 7544603
Add a reference
References: 8 entries
Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.
Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes.
Machesney et al. 1998. Am J Pathol. 152(5):1133-41. PMID: 9588880.
IHC
Activated keratinocytes in the epidermis of hypertrophic scars.
Leigh et al. 1993. Br J Dermatol. 129(2):110-9. PMID: 7544603.
IHC
Monospecific monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) and to keratin 10 as markers of epidermal differentiation.
Add a reference
