Anti-MOZ [127A]
Invented by Prof David Heery from University of Nottingham , Tasneem Ritchie from University of Oxford
Invented at University of Oxford
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 151838 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | Monocytic Leukaemia Zinc Finger Protein, MOZ, MYST3 |
| Reactivity | Human |
| Relevance | MOZ fusion proteins block normal differentiation of myeloid progenitors resulting in AML (acute Myloid Leukaemia).Recombinant fragment of human MOZ (172-321aa) produced as a fusion protein in E. coli. |
| Host | Mouse |
| Immunogen | GST-MOZ (172-321aa) recombinant protein human MOZ |
| Positive Control | HEK293, K562, U937 cells |
| Subclass | IgG3 kappa |
| Molecular Weight (kDa) | 225 |
| Recommended Growing Conditions | The cells are grown in the following medium:- RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT . Ultroser G can be used at 1% if the cells are not growing well.these cell lines HAVE NOT been weaned out of H |
| Notes | Staining pattern: nuclear, suggested dilution 1: 500 |
| Research Area | Epigenetics & Nuclear Signalling |
References: 1 entry
Elizabeth Deeves. 2012. PhD thesis. Novel functions of the MOZ double PHD finder domain.
IP WB
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References: 1 entry
Elizabeth Deeves. 2012. PhD thesis. Novel functions of the MOZ double PHD finder domain.
IP WB
Add a reference
