Anti-Codanin1 [Cod177]
Invented by Tasneem Ritchie from University of Oxford
Invented at University of Oxford
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151783 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | Codanin |
| Synonyms | Codanin 1; Congenital Dyserythropoietic Anemia; Type I; Discs Lost Homolog; PRO1295; CDAN1A; CDA1; DLT |
| Reactivity | Human and Mouse |
| Relevance | Codanin-1 may act as a negative regulator of histone chaperone anti-silencing function 1 (ASF1) in chromatin assembly. Mutations in the codanin-1 gene cause congenital dyserythropoietic anemia 1 (CDA1), which is an autosomal recessive blood disorder characterised by morphological abnormalities of erythroblasts, ineffective erythropoiesis, macrocytic anemia and secondary hemochromatosis. |
| Host | Mouse |
| Immunogen | aa 294-607 of cloned human protein |
| Positive Control | HeLa cells |
| Subclass | IgG2b |
| Myeloma Used | NS0 |
| Research Area | Cardiovascular |
References: 2 entries
Renella et al. 2011. Blood. 117(25):6928-38. PMID: 21364188.
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts.
Europe PMC ID: 21364188
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References: 2 entries
Renella et al. 2011. Blood. 117(25):6928-38. PMID: 21364188.
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts.
Add a reference
