Anti-TAO1 [TAO1 1.2]
Invented by Dr Viji Draviam Sastry from Queen Mary University of London
Invented at University of Cambridge
- Datasheet
- References (2)
- Inventor Info
Info
![Western blot performed using Anti-TAO1 [TAO1 1.2]. HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/8f2e01da-94f9-4b88-9f77-1647acdc8d3d.jpg)
![Western blot performed using Anti-TAO1 [TAO1 1.2]. HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/8f2e01da-94f9-4b88-9f77-1647acdc8d3d.jpg)
![Image thumbnail for Anti-TAO1 [TAO1 1.2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/8f2e01da-94f9-4b88-9f77-1647acdc8d3d.jpg)
| Catalogue Number | 151777 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | TAO1 |
| Reactivity | Human |
| Relevance | TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein |
| Host | Mouse |
| Immunogen | His-tagged recombinant human TAO1 (722-1001) generated in E.coli |
| Positive Control | Lysate from HeLa cell line |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 120 |
| Recommended Growing Conditions | DMEM + 10% FCS |
| Notes |
Staining Pattern: Cellular Cortex Clone also known as TAO_1.2_VMD |
| Research Area | Cancer, Cell Cycle |
References: 2 entries
Shrestha et al. 2014. Open Biol. 4(6):130108. PMID: 24898139.
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.
Europe PMC ID: 24898139
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References: 2 entries
Shrestha et al. 2014. Open Biol. 4(6):130108. PMID: 24898139.
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.
Add a reference
