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Anti-SIGLEC3 [CD33 1C7/1]

Invented by Prof Paul Crocker at University of Dundee

Info

Catalogue Number 151728
Applications ELISA WB
Antigen/Gene or Protein Targets CD33
Synonyms Sialic Acid Binding Ig Like Lectin 12; SIGLECL1; SLG 3; Siglec-12; Siglec-L1; S2V
Reactivity Human
Relevance CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on and a useful marker for peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
Host Mouse
Immunogen Extracellular portion of CD33 fused to the Fc portion of human IgG1
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Research Area Cancer, Cell Type or Organelle Marker, Immunology, Stem Cell Biology

References: 4 entries

Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.

Europe PMC ID: 10206955

Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.

Europe PMC ID: 7718872


Add a reference

References: 4 entries

Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.

Europe PMC ID: 10206955

Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.

Europe PMC ID: 7718872


Add a reference

References: 4 entries

Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.

Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.


Add a reference


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