Anti-S100a9 [2B10]
Invented by Prof Nancy Hogg from Cancer Research UK London Research Institute: Lincoln's Inn Fields
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (11)
- Inventor Info
Info
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| Catalogue Number | 151671 |
| Applications | FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | S100a9 |
| Reactivity | Mouse |
| Relevance | The mAb is specific for mouse S100a9 protein that forms a heterodimer with S100a8 and constitutes 45% of the neutrophil cytosolic protein. The mAb stains neutrophils strongly and monocytes weakly. |
| Host | Rat |
| Immunogen | Recombinant full-length murine S100a9 |
| Positive Control | Neutrophils |
| Subclass | IgG1 kappa |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | RPMI 2% + 10% FCS and weaned down to 5% FCS |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology |
References: 11 entries
Colom et al. 2015. Immunity. 42(6):1075-86. PMID: 26047922.
IF
Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
Europe PMC ID: 26047922
Chen et al. 2015. Mucosal Immunol. 8(2):390-402. PMID: 25160819.
IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.
Europe PMC ID: 25160819
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
Europe PMC ID: 22615129
Voisin et al. 2010. Am J Pathol. 176(1):482-95. PMID: 20008148.
Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation.
Europe PMC ID: 20008148
Young et al. 2007. Br J Pharmacol. 151(5):628-37. PMID: 17471175.
IF
Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice.
Europe PMC ID: 17471175
Hobbs et al. 2003. Mol Cell Biol. 23(7):2564-76. PMID: 12640137.
Myeloid cell function in MRP-14 (S100A9) null mice.
Europe PMC ID: 12640137
Add a reference
References: 11 entries
Colom et al. 2015. Immunity. 42(6):1075-86. PMID: 26047922.
IF
Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
Chen et al. 2015. Mucosal Immunol. 8(2):390-402. PMID: 25160819.
IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
Voisin et al. 2010. Am J Pathol. 176(1):482-95. PMID: 20008148.
Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation.
Young et al. 2007. Br J Pharmacol. 151(5):628-37. PMID: 17471175.
IF
Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice.
Hobbs et al. 2003. Mol Cell Biol. 23(7):2564-76. PMID: 12640137.
Myeloid cell function in MRP-14 (S100A9) null mice.
Add a reference
