Anti-EndoPDI [2E7/7]
Invented by Prof Roy Bicknell from University Of Birmingham
Invented at University of Oxford
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151624 |
| Applications | ELISA IHC IF IP WB |
| Antigen/Gene or Protein Targets | EndoPDI |
| Reactivity | Human |
| Relevance | Endothelial protein disulfide isomerase (EndoPDI; TXNDC5) is a thioredoxin member of the protein disulfide isomerase family of chaperone proteins. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. |
| Host | Mouse |
| Immunogen | Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein. |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | RPMI + 5% FCS |
| Strain | CD1 |
| Notes |
Staining Pattern: Cytoplasmic in primary endothelial cells. Nuclear staining in macrophages as well as breast, renal, and colon cancer cells Suggested Dilution: 1:200 |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Signaling & Signal Transduction |
References: 2 entries
Sullivan et al. 2003. J Biol Chem. 278(47):47079-88. PMID: 12963716.
EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor.
Europe PMC ID: 12963716
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References: 2 entries
Sullivan et al. 2003. J Biol Chem. 278(47):47079-88. PMID: 12963716.
EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor.
Add a reference
