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Anti-Pinin, Polyclonal [Pinin]

Invented by Prof Neil Perkins from University of Newcastle upon Tyne
Invented at University of Dundee

Info

Catalogue Number 151617
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets Pinin
Reactivity Human
Relevance Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.
Host Rabbit
Immunogen Recombinant his-tagged protein
Positive Control U2OS cells
Research Area Cancer, Epigenetics & Nuclear Signalling

References

There are 4 reference entries for this reagent.

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References: 4 entries

Carvalho et al. 2017. J Cell Sci. 130(9):1519-1531. PMID: 28302904.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Regulation of cyclin D1 RNA stability by SNIP1.

Europe PMC ID: 18794151


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References: 4 entries

Carvalho et al. 2017. J Cell Sci. 130(9):1519-1531. PMID: 28302904.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Regulation of cyclin D1 RNA stability by SNIP1.


Add a reference