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Anti-RAET1E [RAET1E 50/3]

Invented at University of Cambridge

Info

Catalogue Number 151541
Applications ELISA FACS IF IP Fn WB
Antigen/Gene or Protein Targets RAET1E
Reactivity Human
Relevance RAET1E (Retinoic Acid Early Transcript 1E), or ULBP4, is a member of the RAET1 family of major histocompatibility complex (MHC) class I-related genes. RAET1E and RAET1G differ from the other RAET1 proteins by having a type I membrane-spanning sequence at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a functional ligand for NKG2D, which causes lymphocyte activation resulting in the secretion of cytokines.
Host Mouse
Immunogen Recombinant His-tagged protein to human extra-cellular domain of RAET1E, grown in E.coli
Positive Control Stable RAET1E cell line
Subclass IgG2b
Research Area Immunology

References

There are 6 reference entries for this reagent.

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References: 6 entries

Cao et al. 2007. J Biol Chem. 282(26):18922-8. PMID: 17470428.

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity.

Europe PMC ID: 17470428

Bacon et al. 2004. J Immunol. 173(2):1078-84. PMID: 15240696.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Europe PMC ID: 15240696

Chalupny et al. 2003. Biochem Biophys Res Commun. 305(1):129-35. PMID: 12732206.

ULBP4 is a novel ligand for human NKG2D.

Europe PMC ID: 12732206


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References: 6 entries

Cao et al. 2007. J Biol Chem. 282(26):18922-8. PMID: 17470428.

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity.

Bacon et al. 2004. J Immunol. 173(2):1078-84. PMID: 15240696.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Chalupny et al. 2003. Biochem Biophys Res Commun. 305(1):129-35. PMID: 12732206.

ULBP4 is a novel ligand for human NKG2D.


Add a reference

Inventor Information

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