Anti-LILRB1 [VMP55]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 151378 |
| Applications | FACS IP WB |
| Antigen/Gene or Protein Targets | Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85) |
| Reactivity | Human |
| Relevance | LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The functional role of LILRB1 has not been fully elucidated. |
| Host | Mouse |
| Immunogen | Hairy cell leukaemia cells |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 120 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Immunology |
References: 8 entries
Lamar et al. 2010. Blood. 115(16):3278-86. PMID: 20194892.
Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.
Europe PMC ID: 20194892
Prod'homme et al. 2007. J Immunol. 178(7):4473-81. PMID: 17372005.
The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.
Europe PMC ID: 17372005
Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908.
Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily.
Europe PMC ID: 10380908
Pulford et al. 1991. Clin Exp Immunol. 85(3):429-35. PMID: 1893623.
A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms.
Europe PMC ID: 1893623
Add a reference
References: 8 entries
Lamar et al. 2010. Blood. 115(16):3278-86. PMID: 20194892.
Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.
Prod'homme et al. 2007. J Immunol. 178(7):4473-81. PMID: 17372005.
The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.
Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908.
Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily.
Pulford et al. 1991. Clin Exp Immunol. 85(3):429-35. PMID: 1893623.
A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms.
Add a reference
