Anti-Rad51, Polyclonal [SWE26]
Invented by Dr Stephen West from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
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Info
| Catalogue Number | 151326 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | Rad51 |
| Reactivity | Human |
| Relevance | Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway. |
| Host | Rabbit |
| Immunogen | Human Rad51 N-Terminal region Peptide C. (VEEESFGPQPISRLE) linked to KLH |
| Formulation | Whole serum |
| Notes | Specific for Rad51 at 100ng compared to equal amount of Dmc1 |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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