Anti-Cdc20 [BA8]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151302 |
| Applications | ELISA FACS WB |
| Antigen/Gene or Protein Targets | Cell division cycle protein 20 (cdc20) |
| Synonyms | APC/C activator protein CDC20; Cell division control protein 20; YGL116W; Cell Division Cycle 20; P55CDC; CDC20 Cell Division Cycle 20; BA276H19.3; CDC20A |
| Reactivity | Xenopus laevis |
| Relevance | Fizzy protein (cdc20) is associated with the activation of the anaphase-promoting complex (APC) at the onset of anaphase. |
| Host | Mouse |
| Immunogen | Peptide from the carboxy terminus of the protein. |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cell Cycle, Protein Degradation |
References: 6 entries
Ohe et al. 2010. Mol Biol Cell. 21(6):905-13. PMID: 20089832.
Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.
Europe PMC ID: 20089832
Sironi et al. 2001. EMBO J. 20(22):6371-82. PMID: 11707408.
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
Europe PMC ID: 11707408
Lorca et al. 1998. EMBO J. 17(13):3565-75. PMID: 9649427.
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts.
Europe PMC ID: 9649427
Add a reference
References: 6 entries
Ohe et al. 2010. Mol Biol Cell. 21(6):905-13. PMID: 20089832.
Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.
Sironi et al. 2001. EMBO J. 20(22):6371-82. PMID: 11707408.
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
Lorca et al. 1998. EMBO J. 17(13):3565-75. PMID: 9649427.
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts.
Add a reference
