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Catalogue Number 151210
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets Cig2
Synonyms Cyc17
Reactivity Schizosaccharomyces pombe
Relevance Cig2 is a fission yeast (S. pombe) B-type S-phase cyclin and is expressed in a sharp spike peaking at G1/S period. Cig2 binds to Cdc2 (Cdk1), and the resulting Cdc2-Cig2 complex controls the G1/S transition of the cell cycle.
Host Mouse
Immunogen S. pombe Cig2 purified protein (bacterial expression)
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM 5% FCS
Research Area Cell Cycle, Cell Signaling & Signal Transduction

References

There are 6 reference entries for this reagent.

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References: 6 entries

Chu et al. 2009. Mol Cell Biol. 29(18):4959-70. PMID: 19596787.

A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast.

Europe PMC ID: 19596787

Chu et al. 2007. Mol Biol Cell. 18(5):1756-67. PMID: 17332498.

Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast.

Europe PMC ID: 17332498

Yamano et al. 2000. Mol Cell. 6(6):1377-87. PMID: 11163211.

The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.

Europe PMC ID: 11163211


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References: 6 entries

Chu et al. 2009. Mol Cell Biol. 29(18):4959-70. PMID: 19596787.

A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast.

Chu et al. 2007. Mol Biol Cell. 18(5):1756-67. PMID: 17332498.

Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast.

Yamano et al. 2000. Mol Cell. 6(6):1377-87. PMID: 11163211.

The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.


Add a reference

Inventor Information