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Anti-ErbB3 [SGP1]

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Info

Catalogue Number 151159
Applications FACS IHC IF IP
Antigen/Gene or Protein Targets ErbB3 (Her3)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB3 is normally found in non-dividing differentiated epithelial cells, neurones and hepatocytes. It has approximately 80% prevalence in a wide variety of tumours of the gastro-intestinal tract, and approximately 20% prevalence in breast cancer.
Host Mouse
Immunogen c-erb B3 protein from transfected human kidney fibroblasts purified by wheatgerm lectin affinity chromatography
Subclass IgG1 kappa
Myeloma Used NS0
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References

There are 5 reference entries for this reagent.

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References: 5 entries

Vollmann-Zwerenz et al. 2010. Cytometry A. 77(4):387-98. PMID: 20151455.

FACS

Multichromatic phenotyping of HER receptor coexpression in breast tumor tissue samples using flow cytometry--possibilities and limitations.

Europe PMC ID: 20151455

Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.

Europe PMC ID: 9771476

Rajkumar et al. 1994. Br J Cancer. 70(3):459-65. PMID: 8080731.

IP

A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines.

Europe PMC ID: 8080731


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References: 5 entries

Vollmann-Zwerenz et al. 2010. Cytometry A. 77(4):387-98. PMID: 20151455.

FACS

Multichromatic phenotyping of HER receptor coexpression in breast tumor tissue samples using flow cytometry--possibilities and limitations.

Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.

Rajkumar et al. 1994. Br J Cancer. 70(3):459-65. PMID: 8080731.

IP

A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines.


Add a reference

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