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Anti-HPV16L1 [CamVir 1]

Invented at University of Cambridge

Info

Catalogue Number 151084
Applications ELISA IHC IP WB
Antigen/Gene or Protein Targets Human papilloma virus type 16, major capsid protein L1 (HPV16 L1)
Reactivity Human papilloma virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein.
Host Mouse
Immunogen A b galactosidase-L1 fusion protein purified by PAGE.
Subclass IgG2a
Molecular Weight (kDa) 56
Myeloma Used NS0
Recommended Growing Conditions DMEM + 5% FCS
Notes CamVir-1 reacts very strongly with biopsy specimens containing HPV-16 or HPV-33, but very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11.
Research Area Cancer, Virology

References

There are 8 reference entries for this reagent.

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References: 8 entries

Day et al. 2012. Clin Vaccine Immunol. 19(7):1075-82. PMID: 22593236.

A human papillomavirus (HPV) in vitro neutralization assay that recapitulates the in vitro process of infection provides a sensitive measure of HPV L2 infection-inhibiting antibodies.

Europe PMC ID: 22593236

Steele et al. 2005. Br J Cancer. 93(2):248-59. PMID: 15986031.

T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.

Europe PMC ID: 15986031

Zhang et al. 1998. Virology. 243(2):423-31. PMID: 9568041.

Expression of human papillomavirus type 16 L1 protein in Escherichia coli: denaturation, renaturation, and self-assembly of virus-like particles in vitro.

Europe PMC ID: 9568041

McLean et al. 1990. J Clin Pathol. 43(6):488-92. PMID: 2166093.

Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus.

Europe PMC ID: 2166093


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References: 8 entries

Day et al. 2012. Clin Vaccine Immunol. 19(7):1075-82. PMID: 22593236.

A human papillomavirus (HPV) in vitro neutralization assay that recapitulates the in vitro process of infection provides a sensitive measure of HPV L2 infection-inhibiting antibodies.

Steele et al. 2005. Br J Cancer. 93(2):248-59. PMID: 15986031.

T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.

Zhang et al. 1998. Virology. 243(2):423-31. PMID: 9568041.

Expression of human papillomavirus type 16 L1 protein in Escherichia coli: denaturation, renaturation, and self-assembly of virus-like particles in vitro.

McLean et al. 1990. J Clin Pathol. 43(6):488-92. PMID: 2166093.

Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus.


Add a reference

Inventor Information

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